Overview

LaboratoryOfPeriodontalBiology

The Laboratory of Periodontal Biology resides in the Department of Oral Biological and Medical Sciences at the Faculty of Dentistry at the University of British Columbia. The UBC campus resides only 30 minutes from the heart of downtown Vancouver. The area is surrounded by the spectacular 763-hectare forest of Pacific Spirit Regional Park and this area provides endless opportunities to explore forested trails. The university has some of the city’s best attractions and recreation facilities, including the Museum of Anthropology, the Chan Centre for the Performing Arts, and the UBC Botanical Garden. Vancouver is located on Canada’s west coast and is one of North America’s most beautiful multicultural cities. It resides between snowcapped North Shore and Coastal mountains and the Pacific Ocean. The city offers limitless opportunities to pursue hiking and mountain biking in the spring and summer, and skiing at nearby North Shore mountains or Whistler-Blackcomb resort in winter.

The general goal of the laboratory is to understand the basic biological mechanisms that regulate wound healing and chronic inflammation. We are specifically interested to uncover how cells interact with extracellular matrix, how extracellular matrix regulates cell functions and how growth factors modulate these processes in normal, chronically inflamed and wounded tissues. To this end, the research teams in the laboratory study 1) the expression and function of integrins in wound healing; 2) the role of the secreted, small leucine rich proteoglycan decorin in the regulation of cell functions and interactions with collagen; 3) the expression, regulation and function of keratinocyte growth factors (KGF). The research teams share common laboratory space and equipment to stimulate exchange of ideas and resources.

Projects