Donald Brunette Symposium: Optimizing the Design of Dental Implants

Donald BrunetteThis is a full-day symposium that honors UBC Professor Don Brunette’s contributions to dental implantology. The 16 speakers at the symposium, who are leading researchers from around the world in immunology, oral biology and implantology, will analyze and review the critical data that enables implant success and informs our thinking on implant failure. The symposium will focus on Don’s research on implant surface topography and how this central element of implant design and engineering impacts the behavior of cells and living tissues, and ultimately, clinical outcomes. In this program the participant will learn of the critical biological processes that are essential for the design and integration of dental implants. In particular, the ideas of Don Brunette and his colleagues in this field will be considered in depth and how this research enabled UBC to become an important centre for implant research.

The symposium is designed for the general practitioner, hygienist, and dental researcher, and will present the current state of the art and science of implantology and related fields, as well as new and exciting developments in the biology that underlies the diagnosis and treatment of peri-implant diseases. The information and approaches considered at this symposium will be useful for practitioners who place and manage the long-term health of dental implants. The course will also be very useful for dentists who address problems associated with failing implants.

In this symposium we will discuss:

  • How Don and his co-workers evaluated implant surface topography and showed how topographical design affects the behavior of the cells that colonize the implant surface, a critical first step in osseointegration
  • Consider the most recent information on regulation of the inflammatory process and how our evolving ideas of inflammation impact our diagnosis and treatment of peri-implant disease
  • Learn how inflammation and surface topography are important considerations in assessing patients at greater risk for implant disease and failure
  • Reflect on the importance of careful analysis of the literature as it applies to dental implants and assess how Don’s ground-breaking book, “Critical Thinking Understanding and Evaluating Dental Research” (Quintessence), has influenced our way of evaluating implants and other dental procedures

The information from this symposium and the current new clinical approaches to implant design that have arisen from Don’s work, are helping to make implant treatment more successful and efficacious for patients around the world.

This symposium will provide 7 hours of instruction for continuing dental education.

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Featured Speakers:

Chris McCulloch, University of Toronto: Data, Don and dental implants
Howard Tenenbaum, University of Toronto: Development of cell culture for studies of periodontal physiology
Connie Eaves, UBC: Stem cells of the blood: progress, challenges and opportunities
Chris Overall, UBC: How proteases in wound healing shape the inflammatory response
Babak Chehroudi, UBC: Optimizing and monitoring tissue-implant integration

Christopher McCulloch

Christopher McCulloch, DDS, Ph.D., FRCD(C)

Dr. McCulloch is the Canada Research Chair and Professor and Director of the Matrix Dynamics Group at the University of Toronto. He focuses on the biology of the extracellular matrix and how the matrix regulates cellular responses in wound healing, inflammatory and fibrotic conditions. Dr. McCulloch is a recognized leader in the field of matrix biology as indicated by continuous funding from the Canadian Institutes of Health Research and other federal agencies in Canada for the last 30 years and the publication of more than 250 peer-reviewed publications in high ranking journals. He has made seminal contributions to the field including the role of the extracellular matrix in in shaping cellular responses of fibroblasts to diabetes and to inflammatory mediators. Dr. McCulloch has also made important contributions in the structure and regulation of the cytoskeleton and how the cytoskeleton affects signaling processes in fibroblasts and contributes to transmission of biophysical signals that alter cellular signaling pathways.

Howard Tenenbaum

Howard Tenenbaum, DDS, Ph.D., FRCD(C)

Dr. Tenenbaum is a Professor of Periodontology, and was Head of that Discipline for 8 years (1997-2005), at the Faculty of Dentistry, University of Toronto. He was also is also Associate Dean for Biological and Diagnostic Sciences for 6 years. He is cross-appointed as a Professor in the Department of Laboratory Medicine and Pathophysiology, Faculty of Medicine, University of Toronto and is Dentist in Chief at Mount Sinai Hospital in Toronto. Dr. Tenenbaum also serves as an FDA panel member for Dental Devices and Drugs (USA) and is Vice-Chair of the Federal Dental Care Advisory Committee (Canada).

Dr. Tenenbaum has had cumulative peer-reviewed research funding since 1987 exceeding $2 million and has lectured internationally on several topics including orofacial pain, cellular biology of bone, and management of refractory periodontal diseases. Dr. Tenenbaum has also had experiments related to bone cell function in microgravity carried out on the US Space Shuttle by Astronaut and Senator John Glenn.

Connie Eaves

Connie J. Eaves, Ph.D., FRS(Canada), FRS (Edinburgh)

Distinguished Scientist, Terry Fox Laboratory, British Columbia Cancer Agency
Professor, Departments of Medical Genetics, Medicine, and Pathology & Laboratory Medicine,
University of British Columbia, Vancouver, Canada

Dr. Eaves holds a BA in Biology & Chemistry and an MSc in Genetics from Queen’s University, Kingston, Ontario, and a PhD in Immunology from the University of Manchester, UK. Following post-doctoral training at the Ontario Cancer Institute under Dr. James Till, she was recruited to develop a research program at the BC Cancer Agency and was cross-appointed in Medical Genetics at UBC. In 1981, she and her husband started the Terry Fox Laboratory at the BC Cancer Agency and together built an internationally recognized research program in normal and cancer stem cell biology, leukemia, and breast stem cell biology. She has published more than 480 scientific papers and has a long and continuing track record both as a scientific leader and as a conscientious mentor of trainees at all levels. She has also been a major contributor to science policy and development in Canada and globally and has received numerous national and international awards for her many accomplishments.

Christopher Overall

Christopher Overall, BDS, B.Sc., MDS, Ph.D.

Dr. Overall is a Professor and Tier 1 Canada Research Chair in Proteinase Proteomics and Systems Biology at the University of British Columbia, Centre for Blood Research. He completed his undergraduate, Honors Science and Masters degrees at the University of Adelaide, South Australia; his Ph.D. in Biochemistry at the University of Toronto; and was a MRC Centennial Fellow in his post-doctoral work with Dr. Michael Smith, Nobel Laureate, Biotechnology Laboratory, University of British Columbia (UBC). On Sabbatical in 1997-1998 he was a Visiting Senior Scientist at British Biotech Pharmaceuticals, Oxford, UK and in 2004/2008 he was a Visiting Senior Scientist at the Expert Protease Platform, Novartis Pharmaceuticals, Basel, Switzerland. At the Freiburg Institute for Advanced Studies, Albert-Ludwigs Universität Freiburg, Germany he was an External Senior Fellow, and in November 2014 was appointed as an Honorary Professor, Albert-Ludwigs Universität Freiburg. Dr. Overall was awarded the Institute of Musculoskeletal Health and Arthritis CIHR Award as 2002 CIHR Scientist of the Year, the UBC Killam Senior Researcher Award (Science) 2005, and was the Chair of the 2003 Matrix Metalloproteinase Gordon Research Conference and the 2010 Protease Gordon Research Conference. He was elected to the HUPO Council and to the Executive Committee of the Chromosome–Centric Human proteome Project (CHPP) in 2014. With over 13,521 citations for his 214 papers (since 2000 his papers have been cited >8,813 times) and with an h factor of 63 he is a highly influential scientist in the field. Professor Overall is also the pioneer of degradomics, a term he coined. With 21 Nature Review, Nature Journal, Cell Journal, Science and Science Signaling papers he is a leader in the field, which was recently recognized by the International Society of Proteolysis with a Lifetime Achievement Award in 2011; by the Matrix Biology Society of Australia and New Zealand with the 2012 Barry Preston Award; in 2013 by the IADR Distinguished Scientist Award for Research in Oral Biology; and in 2014 by the Tony Pawson Canadian National Proteomics Network Award for Outstanding Contribution and Leadership to the Canadian Proteomics Community. He is an Associate Editor of the Journal of Proteome Research and on the Editorial Boards of the Journal of Molecular Cellular Proteomics and Biological Chemistry and the Advisory Committee of the International Union of Basic and Clinical Pharmacology.

Babak Chehroudi

Babak Chehroudi, DMD, Ph.D.

Dr. Chehroudi is a Clinical Professor in the department of Oral Health Sciences of the University of British Columbia. He completed his dental training at the National University of Iran in 1983. In 1986, he started research training in the area of cellular interactions with biomaterials under the supervision of Drs. Donald Brunette and Timothy Gould. He obtained his Ph.D. degree in Oral Biology at the University of British Columbia in 1991. He has more than 80 publications in peer-reviewed journals and book chapters in the field of biomaterials, implants surface design, dental implant stability, and computer-aided educational models in dental anatomy. His current collaborative research with the Robotic Engineering division of Simon Fraser University explores applications of acoustics and vibration analysis in designing new generation of smart dental handpieces and devices capable of measuring dental implant stability. Dr. Chehroudi also teaches extensively in didactic and clinical courses, for both the DMD and postgraduate specialty programs at UBC.


Dr. Yoshihiro Abiko, Professor, School of Dentistry, Health Sciences University of Hokkaido (Japan)
Dr. George Beagrie, Dean Emeritus, UBC Faculty of Dentistry
Dr. Marcia Boyd, Dean Emerita, UBC Faculty of Dentistry
Dr. Laisheng (Lee) Chou, Professor, Boston University Henry M. Goldman School of Dental Medicine
Dr. Tetsuya Goto, Professor, Kagoshima University (Japan)
Dr. Timothy Gould, British Columbia Dental Association
Dr. Douglas Hamilton, Associate Professor, Schulich School of Medicine and Dentistry, Western University
Dr. Emil Svoboda, Private practice, Brampton, ON
Dr. Douglas Waterfield, Professor Emeritus, UBC Faculty of Dentistry
Dr. Marco Wieland, Senior Consultant, Altran Switzerland
Dr. Ken Yaegaki, Professor and Head, Dept. of Oral Health, Nippon Dental University (Japan)

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Dates and Schedule:

• Thursday, April 14, 2016

4:30 pm: Welcome reception and cocktail

• Friday April 15, 2016 (Symposium from 7:00 am – 5:30 pm)

7:00 am – 8:00 am: Registration and continental breakfast
8:00 am – 8:30 am: Opening remarks
8:30 am – 12:00 pm: Presentations
12:00 pm – 1:00 pm: Lunch
1:00 pm – 5:00 pm: Presentations
6:00 pm: Dinner (full course)

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Sage Bistro, 6331 Crescent Road, Vancouver, BC V6T 1Z1
Parking available at Rose Garden Parkade, 6278 North West Marine Drive (at Main Mall)

Brunette Symposium Map

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Registration Fee and Deadline:


Final registration deadline: April 4, 2016

Click here to register >>

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Hotel Accommodations:

For out-of-town attendees, options for hotel accommodations include:

1. West Coast Suites (on the UBC campus), 5961 Student Union Boulevard, Vancouver, BC V6T 2C9

2. TRIUMF House (on the UBC campus), 5835 Thunderbird Boulevard, Vancouver, BC V6T 2L6

3. Sheraton Wall Centre (Downtown Vancouver), 1088 Burrard Street, Vancouver, BC V6Z 2R9
UBC rate is available, use code # 377098 when booking online

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Diamond Sponsors:

This event is generously sponsored by Straumann and Quintessence Publishing.

Straumann Logo

Quintessence Publishing Logo


Emerald Sponsor:

Citagenix Logo


Pearl Sponsor:

Citagenix Logo

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For further information, please contact Hugh Kim.